Biotechs explore the next generation of inflammasome targets, with caution
Inflammasomes: mechanism of action, role in disease, and therapeutics.
The intra- and extracellular functions of ASC specks.
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Inflammasomes and autoimmunity.
IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis
A molecular platform in neurons regulates inflammation after spinal cord injury.
Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury.
Exosome-mediated inflammasome signaling after central nervous system injury.
Traumatic Brain Injury-Induced Acute Lung Injury: Evidence for Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis.
Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury.
Therapeutics targeting the inflammasome after central nervous system injury.
Inflammasome Proteins As Biomarkers of Multiple Sclerosis.
Inflammasome proteins as biomarkers of traumatic brain injury.
Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response.