Variant Pharmaceuticals Has a New Name - ZyVersa Therapeutics, Inc.
WESTON, Fla., Sept. 12, 2019 /PRNewswire/ -- ZyVersa Therapeutics, Inc., (ZyVersa) a clinical stage specialty biopharmaceutical company developing first-in-class drugs for treatment of inflammatory and renal diseases, is pleased to announce that the August 15th edition of BIOCENTURY Innovations reported ZyVersa's perspectives on inflammasomes. The article, Biotechs explore the next generation of inflammasome targets, with caution, notes that "inflammasome complexes have come to the fore as attractive targets because they sit upstream of cytokines, meaning interfering with them can cut off inflammation at the source."
The article's author, Lauren Martz, Associate Editor, reported on ZyVersa's stated rationale for targeting the adaptor ASC component of inflammasomes, including:
A copy of the BIOCENTURY Innovations article can be found on the ZyVersa website: Click Here.
About IC 100
IC 100 is a monoclonal antibody that uniquely inhibits the adaptor ASC component of multiple types of inflammasomes. Because pathogenesis of numerous chronic inflammatory diseases involves activation of more than one type of inflammasome (e.g. the NLRP3 inflammasome), IC 100 may be more effective for treating a broad range of inflammatory diseases than targeting just one.
By inhibiting ASC, IC 100 blocks inflammasome formation, with potential to block initiation of the inflammatory cascade. By inhibiting the ASC component of ASC Specks, IC 100 disrupts the structure and function of ASC Specks, with potential to block perpetuation of the inflammatory response responsible for chronic, damaging inflammation. For more information about IC 100's mechanism of action, please review the infographic by Clicking Here.
About ZyVersa Therapeutics, Inc.
ZyVersa is a clinical stage specialty biopharmaceutical company leveraging advanced, proprietary technologies to develop first-in-class drugs. Our focus is on patients with inflammatory or renal diseases who have significant unmet medical needs. Our clinical pipeline includes a phase 2a-ready asset, VAR 200, a cholesterol efflux mediator for treatment of a rare kidney disease, focal segmental glomerulosclerosis (FSGS), and a novel inflammasome inhibitor with potential to treat multiple inflammatory diseases. For more information, please visit www.zyversa.com.
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SOURCE ZyVersa Therapeutics, Inc.